|  Tissue Specificity  |   Kidney, brain, and intestine.  |  
  |  Post Translational Modifications  |   Synthesized as a 74-kDa cytosolic precursor which is proteolytically processed by the mitochondrial-processing peptidase (MPP) via a 72-kDa intermediate to yield the mature mitochondrial 68- and 65-kDa subunits.  |  
  |  Function  |   Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain.  |  
  |  Protein Name  |   Glutaminase Kidney Isoform - MitochondrialGlsK-GlutaminaseL-Glutamine Amidohydrolase Cleaved Into - Glutaminase Kidney Isoform - Mitochondrial 68 Kda Chain - Glutaminase Kidney Isoform - Mitochondrial 65 Kda Chain  |  
  |  Database Links  |   Reactome: R-RNO-210500Reactome: -RNO-5628897Reactome: -RNO-8964539  |  
  |  Cellular Localisation  |   Isoform 1: MitochondrionCytoplasmCytosolThe 74-Kda Cytosolic Precursor Is Translocated Into The Mitochondria And Processed Via A 72-Kda Intermediate To Yield The Mature 68 And 65-Kda SubunitsGlutaminase Kidney IsoformMitochondrial 68 Kda Chain: Mitochondrion MatrixProduced By The Proteolytic Processing Of The 74-Kda Cytosolic PrecursorMitochondrial 65 Kda Chain: Mitochondrion Matrix  |  
  |  Alternative ELISA Names  |   Glutaminase Kidney Isoform - Mitochondrial ELISA kitGls ELISA kitK-Glutaminase ELISA kitL-Glutamine Amidohydrolase Cleaved Into - Glutaminase Kidney Isoform - Mitochondrial 68 Kda Chain - Glutaminase Kidney Isoform - Mitochondrial 65 Kda Chain ELISA kitGls ELISA kit  |  
  |  output  |    |  
 
Information sourced from Uniprot.org