| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.01 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured by its ability to neutralize Activin-mediated inhibition on MPC-11 cell proliferation. The ED50 for this effect is 23.68-94.70 ng/mL, corresponding to a specific activity of 1.06×104~4.22×104 units/mg in the |
| Gene Symbol: | Fst |
| Gene ID: | 24373 |
| Uniprot ID: | FST_RAT |
| Immunogen Region: | Met1-Trp344 |
| Immunogen: | Recombinant Rat Follistatin/FST Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Trp344) of Rat Follistatin/FST (Accession #NP_036693.1) fused with a His tag at the C-terminus. |
| Immunogen Sequence: | MTARGAAGRCPSSTWLGSRL LLVCLLMSRSIAKEVSEHCS HMIGNGHLKVLQQLIDSQME TSCQIAFEFVDQEQLDDPVC YLKKAFFLVQDIIDETMRFK DNTPNANATERLQELSNNLN SCFTKDYEEQNKACVRTFHE TPLQLLEKIKNFFNETKNLL EKDWNIFTKNCNNSFAKCSS RDVVTKP |
| Function | Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). |
| Protein Name | FollistatinFsActivin-Binding Protein |
| Database Links | Reactome: R-RNO-2473224 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Follistatin proteinFs proteinActivin-Binding Protein proteinFst protein |
Information sourced from Uniprot.org