Rat EMMPRIN (Extracellular Matrix Metalloproteinase Inducer) Sandwich ELISA Kit (STJE0008638)
SPECIFICATIONS
General Information
| Short Description | This EMMPRIN Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma, lung lavage fluid or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 5.5pg/mL |
| Detection Limit | 15.6-1000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Bsg |
| Gene ID | 25246 |
| Uniprot ID | BASI_RAT |
| Sample Type | serum, plasma, lung lavage fluid or other biological fluids. |
Additional Info
| Tissue Specificity | Isoform 2: Expressed in the skeletal muscle, liver, small intestine, kidney, testis, brain, heart and spleen. Also present in various immature cells and endothelia. |
| Post Translational Modifications | |
| Function | Isoform 1: Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. Isoform 2: Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells. Plays an important role in targeting the monocarboxylate transporters SLC16A1/GLUT1 and SLC16A3 to the plasma membrane. Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling. Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA and KDR/VEGFR2 in endothelial cells. Plays an important role in spermatogenesis.mediates interactions between germ cells and Sertoli cell and is essential for the development/differentiation of germ cells to round spermatids. |
| Protein Name | BasiginGlycoprotein Ce9Ox-47 AntigenCd Antigen Cd147 |
| Database Links | Reactome: R-RNO-1474228Reactome: -RNO-210991Reactome: -RNO-216083Reactome: -RNO-433692Reactome: -RNO-9749641 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinPhotoreceptor Inner SegmentCell ProjectionCiliumPhotoreceptor Outer SegmentIsoform 2: Cell MembraneEndoplasmic Reticulum MembraneBasolateral Cell Membrane |
| Alternative ELISA Names | Basigin ELISA kitGlycoprotein Ce9 ELISA kitOx-47 Antigen ELISA kitCd Antigen Cd147 ELISA kitBsg ELISA kit |
| output |
Information sourced from Uniprot.org