Rat DUOX2 (Dual Oxidase 2) Sandwich ELISA Kit (STJE0008529)
SPECIFICATIONS
General Information
| Short Description | This DUOX2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 0.058ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Duox2 |
| Gene ID | 79107 |
| Uniprot ID | DUOX2_RAT |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in colon, duodenum, rectum and thyroid. |
| Post Translational Modifications | N-glycosylated. |
| Function | Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain. |
| Protein Name | Dual Oxidase 2Large Nox 2Long Nox 2Nadh/Nadph Thyroid Oxidase Thox2Thyroid Oxidase 2 |
| Database Links | Reactome: R-RNO-209968 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinCell JunctionLocalizes To The Apical Membrane Of Epithelial CellsLocalizes On Internal Membrane Structures Under Resting ConditionsTranslocates To The Plasma Membrane And Cell-Cell Junctions Upon Challenge With Enteric Pathogens |
| Alternative ELISA Names | Dual Oxidase 2 ELISA kitLarge Nox 2 ELISA kitLong Nox 2 ELISA kitNadh/Nadph Thyroid Oxidase Thox2 ELISA kitThyroid Oxidase 2 ELISA kitDuox2 ELISA kitLnox2 ELISA kitThox2 ELISA kit |
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Information sourced from Uniprot.org