| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Rat CD2 (LFA-2)-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Gene Symbol: | Cd2 |
| Gene ID: | 497761 |
| Uniprot ID: | CD2_RAT |
| Immunogen Region: | ECD |
| Immunogen: | Optimized DNA sequence encoding extracellular domain of Rat CD2 (LFA-2) including an IgG1 Fc C-terminal tag was expressed in HEK293 cells. NA |
| Function | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. |
| Protein Name | T-Cell Surface Antigen Cd2Lfa-2Lfa-3 ReceptorOx-34 AntigenT-Cell Surface Antigen T11/Leu-5Cd Antigen Cd2 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | T-Cell Surface Antigen Cd2 proteinLfa-2 proteinLfa-3 Receptor proteinOx-34 Antigen proteinT-Cell Surface Antigen T11/Leu-5 proteinCd Antigen Cd2 proteinCd2 protein |
Information sourced from Uniprot.org