| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: |
Crp |
| Gene ID: |
25419 |
| Uniprot ID: |
CRP_RAT |
| Immunogen: |
Recombinant Rat C-Reactive Protein/CRP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (His20-Ser230) of rat C-Reactive Protein/CRP (Accession #NP_058792.1) fused with a 6×His tag at the C-terminus |
| Immunogen Sequence: |
HEDMSKQAFVFPGVSATAYV SLEAESKKPLEAFTVCLYAH ADVSRSFSIFSYATKTSFNE ILLFWTRGQGFSIAVGGPEI LFSASEIPEVPTHICATWES ATGIVELWLDGKPRVRKSLQ KGYIVGTNASIILGQEQDSY GGGFDANQSLVGDIGDVNMW DFVLSPEQINAVYVGRVFSP NVLNWRALKYETHGDVFIKP QLWPLTDCCES |
| Post Translational Modifications | The last two cysteines are involved either in interchain disulfide bonds or in an intrachain bond. |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Protein Name | C-Reactive Protein |
| Database Links | Reactome: R-RNO-173623 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-Reactive Protein proteinCrp proteinPtx1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
