Rat ADAMTS7 (A Disintegrin And Metalloproteinase With Thrombospondin 7) Sandwich ELISA Kit (STJE0006907)
SPECIFICATIONS
General Information
| Short Description | This ADAMTS7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 0.058ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Adamts7 |
| Gene ID | 315879 |
| Uniprot ID | ATS7_RAT |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Detected in liver, ovary, kidney, testicle, lung and embryo. |
| Post Translational Modifications | Glycosylated. Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members. Can also be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs. N- and C-glycosylations can also facilitate secretion. O-glycosylated proteoglycan.contains chondroitin sulfate. May be cleaved by a furin endopeptidase. The precursor is sequentially processed. |
| Function | Metalloprotease. Was previously shown to degrade COMP. However, a later study found no activity against COMP. |
| Protein Name | A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7Adam-Ts 7Adam-Ts7Adamts-7 |
| Database Links | Reactome: R-RNO-5173214 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixAlso Found Associated With The External Cell Surface |
| Alternative ELISA Names | A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7 ELISA kitAdam-Ts 7 ELISA kitAdam-Ts7 ELISA kitAdamts-7 ELISA kitAdamts7 ELISA kit |
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Information sourced from Uniprot.org