| Short Description : | Rabbit Rabbit IgG antibody for use in IP and ChIP in rabbit samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IP/ChIP |
| Host: | Rabbit |
| Reactivity: | Rabbit |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Potein A/G purification |
| Dilution Range: | IP:0.5ug-4ug antibody for 200ug-400ug extracts of whole cellsChIP:5 Mu g antibody for 10 Mu g-15 Mu g of Chromatin |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Specificity: | None |
| Background | The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body s response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. |
Information sourced from Uniprot.org
