Rabbit Anti-Mouse IgE Fc (50-388 aa) antibody {HRP} (STJS001223)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationHRP
IsotypeIgG
General Information
| Short Description | HRP-conjugated rabbit monoclonal anti-Mouse IgE Fc 50-388 aa secondary antibody. For use in most research applications. |
| Applications | ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM15550 |
| Isotype | IgG |
| Conjugation | HRP |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | ELISA: 1:5000-1:10000 |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Immunogen Region | 50-388 aa |
| Immunogen Sequence | FNESRTILVRPVNITEPTLE LLHSSCDPNAFHSTIQLYCF IYGHILNDVSVSWLMDDREI TDTLAQTVLIKEEGKLASTC SKLNITEQQWMSESTFTCKV TSQGVDYLAHTRRCPDHEPR GVITYLIPPSPLDLYQNGAP KLTCLVVDLESEKNVNVTWN QEKKTSVSASQWYTKHHNNA TTSITSILPVVAKDWIEGYG YQCIVDHPDFPKPIVRSITK TPGQRSAPEVYVFPPPEEE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 50-388 of mouse IgE. (AAZ05128.1). |
Additional Info
| Background | Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens 1, 2. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V- (D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen |
Information sourced from Uniprot.org