PP2A-alpha Blocking Peptide for STJ505945 peptide (STJ505728)

SKU:
STJ505728-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: PP2A-alpha Blocking Peptide for STJ505945 is synthetically produced from the 410-486 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PPP2R5A
Gene ID: 5525
Uniprot ID: 2A5A_HUMAN
Immunogen Region: 410-486
Specificity: This blocking peptide is recommended for use in combination with PP2A-alpha antibody, STJ505945
Immunogen: Synthetic peptide taken within amino acid region 410-486 on human Serine/Threonine-Protein Phosphatase 2A, B56-Alpha subunit.
Tissue Specificity Widely expressed with the highest expression in heart and skeletal muscle.
Post Translational Modifications Phosphorylated on serine residues.
Function The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Peptide Name Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Alpha Isoform
Pp2a B Subunit Isoform B'-Alpha
Pp2a B Subunit Isoform B56-Alpha
Pp2a B Subunit Isoform Pr61-Alpha
Pr61alpha
Pp2a B Subunit Isoform R5-Alpha
Database Links Reactome: R-HSA-141444
Reactome: R-HSA-195253
Reactome: R-HSA-196299
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-389513
Reactome: R-HSA-432142
Reactome: R-HSA-4641262
Reactome: R-HSA-5339716
Reactome: R-HSA-5358747
Reactome: R-HSA-5358749
Reactome: R-HSA-5358751
Reactome: R-HSA-5358752
Reactome: R-HSA-5467337
Reactome: R-HSA-5467340
Reactome: R-HSA-5467348
Reactome: R-HSA-5663220
Reactome: R-HSA-5673000
Reactome: R-HSA-5675221
Reactome: R-HSA-6811558
Reactome: R-HSA-68877
Reactome: R-HSA-9648025
Cellular Localisation Cytoplasm
Nucleus
Chromosome
Centromere
From Mitotic Prophase To Metaphase
Localizes At The Inner Centromere Between A Pair Of Sister Kinetochores
Decreased Expression At The Onset Of Anaphase
Alternative Peptide Names Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Alpha Isoform protein
Pp2a B Subunit Isoform B'-Alpha protein
Pp2a B Subunit Isoform B56-Alpha protein
Pp2a B Subunit Isoform Pr61-Alpha protein
Pr61alpha protein
Pp2a B Subunit Isoform R5-Alpha protein
PPP2R5A protein

Information sourced from Uniprot.org

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