| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
PP1R3A Blocking Peptide for STJ506059 is synthetically produced from the 830-880 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
PPP1R3A |
| Gene ID: |
5506 |
| Uniprot ID: |
PPR3A_HUMAN |
| Immunogen Region: |
830-880 |
| Specificity: |
This blocking peptide is recommended for use in combination with PP1R3A antibody, STJ506059 |
| Immunogen: |
Synthetic peptide taken within amino acid region 830-880 on mouse Protein Phosphatase 1 Regulatory Subunit 3A. |
| Tissue Specificity | Skeletal muscle and heart. |
| Post Translational Modifications | Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase. |
| Function | Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase. |
| Peptide Name | Protein Phosphatase 1 Regulatory Subunit 3aProtein Phosphatase 1 Glycogen-Associated Regulatory SubunitProtein Phosphatase Type-1 Glycogen Targeting SubunitRg1 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Peptide Names | Protein Phosphatase 1 Regulatory Subunit 3a proteinProtein Phosphatase 1 Glycogen-Associated Regulatory Subunit proteinProtein Phosphatase Type-1 Glycogen Targeting Subunit proteinRg1 proteinPPP1R3A proteinPP1G protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
