| Tissue Specificity | Skeletal muscle and heart. |
| Post Translational Modifications | Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase. |
| Function | Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase. |
| Peptide Name | Protein Phosphatase 1 Regulatory Subunit 3aProtein Phosphatase 1 Glycogen-Associated Regulatory SubunitProtein Phosphatase Type-1 Glycogen Targeting SubunitRg1 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Peptide Names | Protein Phosphatase 1 Regulatory Subunit 3a proteinProtein Phosphatase 1 Glycogen-Associated Regulatory Subunit proteinProtein Phosphatase Type-1 Glycogen Targeting Subunit proteinRg1 proteinPPP1R3A proteinPP1G protein |
Information sourced from Uniprot.org
