Post Translational Modifications | Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated. |
Function | Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. |
Peptide Name | Atrial Natriuretic Peptide Receptor 2Atrial Natriuretic Peptide Receptor Type BAnp-BAnpr-BNpr-BGuanylate Cyclase BGc-B |
Database Links | Reactome: R-HSA-5578768 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Peptide Names | Atrial Natriuretic Peptide Receptor 2 proteinAtrial Natriuretic Peptide Receptor Type B proteinAnp-B proteinAnpr-B proteinNpr-B proteinGuanylate Cyclase B proteinGc-B proteinNPR2 proteinANPRB protein |
Information sourced from Uniprot.org