Applications: |
WB |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
PGCB Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
Dilution Range: |
WB: 1:500 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Post Translational Modifications | Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated. |
Function | Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. |
Peptide Name | Atrial Natriuretic Peptide Receptor 2Atrial Natriuretic Peptide Receptor Type BAnp-BAnpr-BNpr-BGuanylate Cyclase BGc-B |
Database Links | Reactome: R-HSA-5578768 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Peptide Names | Atrial Natriuretic Peptide Receptor 2 proteinAtrial Natriuretic Peptide Receptor Type B proteinAnp-B proteinAnpr-B proteinNpr-B proteinGuanylate Cyclase B proteinGc-B proteinNPR2 proteinANPRB protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance