PDE4D7 Positive Control for STJ502342 peptide (STJ504652)

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STJ504652-5

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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: PDE4D7 Positive Control for STJ502342 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Pde4d
Gene ID: 238871
Uniprot ID: PDE4D_MOUSE
Specificity: This is positive control is recommended for use in combination with PDE4D7 antibody STJ502342.
Tissue Specificity Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis.
Post Translational Modifications Sumoylation of long isoforms by PIAS4 augments their activation by PKA phosphorylation and represses their inhibition by ERK phosphorylation.
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Peptide Name 3' -5'-Cyclic-Amp Phosphodiesterase 4d
Dpde3
Camp-Specific Phosphodiesterase 4d
Database Links Reactome: R-MMU-180024
Reactome: -MMU-418555
Cellular Localisation Cytoplasm
Membrane
Cytoskeleton
Microtubule Organizing Center
Centrosome
Apical Cell Membrane
Colocalized With Shank2 To The Apical Membrane Of Colonic Crypt Cells
Found In The Soluble Fraction
Associated With Membranes
And Associated With The Cytoskeleton And The Centrosome
Alternative Peptide Names 3' -5'-Cyclic-Amp Phosphodiesterase 4d protein
Dpde3 protein
Camp-Specific Phosphodiesterase 4d protein
Pde4d protein

Information sourced from Uniprot.org

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