| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
PDE4D Blocking Peptide is synthetically produced from the C-Term sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
PDE4B |
| Gene ID: |
5142 |
| Uniprot ID: |
PDE4B_HUMAN |
| Immunogen Region: |
C-Term |
| Immunogen: |
C-terminal cyclic peptide unique to all PDED subtypes variants. |
| Tissue Specificity | Expressed in brain, heart, lung and skeletal muscle. Expressed in white blood cells. Isoform PDE4B5: Brain-specific isoform. |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. |
| Peptide Name | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4bDpde4Pde32 |
| Database Links | Reactome: R-HSA-180024 Q07343-3 |
| Cellular Localisation | Isoform Pde4b5: CytoplasmCell Membrane |
| Alternative Peptide Names | Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b proteinDpde4 proteinPde32 proteinPDE4B proteinDPDE4 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
