PDE4B Positive Control for STJ502321 peptide (STJ505275)

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STJ505275-5

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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: PDE4B Positive Control for STJ502321 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500-1:1, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PDE4B
Gene ID: 5142
Uniprot ID: PDE4B_HUMAN
Specificity: This is positive control is recommended for use in combination with PDE4B antibody STJ502321.
Tissue Specificity Expressed in brain, heart, lung and skeletal muscle. Expressed in white blood cells. Isoform PDE4B5: Brain-specific isoform.
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Peptide Name Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b
Dpde4
Pde32
Database Links Reactome: R-HSA-180024 Q07343-3
Cellular Localisation Isoform Pde4b5: Cytoplasm
Cell Membrane
Alternative Peptide Names Camp-Specific 3' -5'-Cyclic Phosphodiesterase 4b protein
Dpde4 protein
Pde32 protein
PDE4B protein
DPDE4 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance