PBR Positive Control peptide (STJ505239)

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STJ505239-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : PBR Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: TSPO
Gene ID: 706
Uniprot ID: TSPO_HUMAN
Tissue Specificity Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.
Function Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides.
Peptide Name Translocator Protein
Mitochondrial Benzodiazepine Receptor
Pkbs
Peripheral-Type Benzodiazepine Receptor
Pbr
Database Links Reactome: R-HSA-196108
Cellular Localisation Mitochondrion Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Translocator Protein protein
Mitochondrial Benzodiazepine Receptor protein
Pkbs protein
Peripheral-Type Benzodiazepine Receptor protein
Pbr protein
TSPO protein
BZRP protein
MBR protein

Information sourced from Uniprot.org

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