| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | PBR Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | TSPO |
| Gene ID: | 706 |
| Uniprot ID: | TSPO_HUMAN |
| Tissue Specificity | Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids. |
| Function | Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor.can also bind isoquinoline carboxamides. |
| Peptide Name | Translocator Protein Mitochondrial Benzodiazepine Receptor Pkbs Peripheral-Type Benzodiazepine Receptor Pbr |
| Database Links | Reactome: R-HSA-196108 |
| Cellular Localisation | Mitochondrion Membrane Multi-Pass Membrane Protein |
| Alternative Peptide Names | Translocator Protein protein Mitochondrial Benzodiazepine Receptor protein Pkbs protein Peripheral-Type Benzodiazepine Receptor protein Pbr protein TSPO protein BZRP protein MBR protein |
Information sourced from Uniprot.org