| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
PAR3 Positive Control for STJ502117 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:5, 000 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
F2rl3 |
| Gene ID: |
14065 |
| Uniprot ID: |
PAR4_MOUSE |
| Specificity: |
This is positive control is recommended for use in combination with PAR3 antibody STJ502117. |
| Tissue Specificity | Highly expressed in the spleen. Slight expression in the heart, lung, skeletal muscle and kidney. No detectable expression in brain, liver or testis. Also detected in platelets. |
| Post Translational Modifications | A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. |
| Function | Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. |
| Peptide Name | Proteinase-Activated Receptor 4Par-4Coagulation Factor Ii Receptor-Like 3Thrombin Receptor-Like 3 |
| Database Links | Reactome: R-MMU-375276Reactome: -MMU-416476Reactome: -MMU-456926 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Proteinase-Activated Receptor 4 proteinPar-4 proteinCoagulation Factor Ii Receptor-Like 3 proteinThrombin Receptor-Like 3 proteinF2rl3 proteinPar4 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
