PAR3 Positive Control for STJ502117 peptide (STJ504571)

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STJ504571-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : PAR3 Positive Control for STJ502117 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:5, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: F2rl3
Gene ID: 14065
Uniprot ID: PAR4_MOUSE
Specificity: This is positive control is recommended for use in combination with PAR3 antibody STJ502117.
Tissue Specificity Highly expressed in the spleen. Slight expression in the heart, lung, skeletal muscle and kidney. No detectable expression in brain, liver or testis. Also detected in platelets.
Post Translational Modifications A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
Function Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
Peptide Name Proteinase-Activated Receptor 4
Par-4
Coagulation Factor Ii Receptor-Like 3
Thrombin Receptor-Like 3
Database Links Reactome: R-MMU-375276
Reactome: -MMU-416476
Reactome: -MMU-456926
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Proteinase-Activated Receptor 4 protein
Par-4 protein
Coagulation Factor Ii Receptor-Like 3 protein
Thrombin Receptor-Like 3 protein
F2rl3 protein
Par4 protein

Information sourced from Uniprot.org

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