| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
PAR3 Blocking Peptide for STJ502116 is synthetically produced from the 1-100 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
F2rl3 |
| Gene ID: |
14065 |
| Uniprot ID: |
PAR4_MOUSE |
| Immunogen Region: |
1-100 |
| Specificity: |
This blocking peptide is recommended for use in combination with PAR3 antibody, STJ502116 |
| Immunogen: |
Synthetic peptide taken within amino acid region 1-100 on mouse Proteinase-activated receptor 3 protein. |
| Tissue Specificity | Highly expressed in the spleen. Slight expression in the heart, lung, skeletal muscle and kidney. No detectable expression in brain, liver or testis. Also detected in platelets. |
| Post Translational Modifications | A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. |
| Function | Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. |
| Peptide Name | Proteinase-Activated Receptor 4Par-4Coagulation Factor Ii Receptor-Like 3Thrombin Receptor-Like 3 |
| Database Links | Reactome: R-MMU-375276Reactome: -MMU-416476Reactome: -MMU-456926 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Proteinase-Activated Receptor 4 proteinPar-4 proteinCoagulation Factor Ii Receptor-Like 3 proteinThrombin Receptor-Like 3 proteinF2rl3 proteinPar4 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
