| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
PACAP Blocking Peptide is synthetically produced from the 125-176 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
ADCYAP1 |
| Gene ID: |
116 |
| Uniprot ID: |
PACA_HUMAN |
| Immunogen Region: |
125-176 |
| Immunogen: |
Synthetic peptide taken within amino acid region 125-176 on human Pituitary adenylate cyclase-activating polypeptide protein. |
| Function | Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. |
| Peptide Name | Pituitary Adenylate Cyclase-Activating PolypeptidePacap Cleaved Into - Pacap-Related PeptidePrp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27Pacap-27Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38Pacap-38Pacap38 |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Secreted |
| Alternative Peptide Names | Pituitary Adenylate Cyclase-Activating Polypeptide proteinPacap Cleaved Into - Pacap-Related Peptide proteinPrp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27 proteinPacap-27 proteinPacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38 proteinPacap-38 proteinPacap38 proteinADCYAP1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
