PACAP Blocking Peptide peptide (STJ505620)

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STJ505620-250
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Short Description :PACAP Blocking Peptide is synthetically produced from the 125-176 sequence and is suitable for use in western blot applications.
Applications:Immunodepletion/Immunocompetition
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation:Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol:ADCYAP1
Gene ID:116
Uniprot ID:PACA_HUMAN
Immunogen:Synthetic peptide taken within amino acid region 125-176 on human Pituitary adenylate cyclase-activating polypeptide protein.
Immunogen Region:125-176
Function Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.
Peptide Name Pituitary Adenylate Cyclase-Activating Polypeptide
Pacap Cleaved Into - Pacap-Related Peptide
Prp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27
Pacap-27
Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38
Pacap-38
Pacap38
Database Links Reactome: R-HSA-187024
Reactome: R-HSA-418555
Reactome: R-HSA-420092
Cellular Localisation Secreted
Alternative Peptide Names Pituitary Adenylate Cyclase-Activating Polypeptide protein
Pacap Cleaved Into - Pacap-Related Peptide protein
Prp-48 - Pituitary Adenylate Cyclase-Activating Polypeptide 27 protein
Pacap-27 protein
Pacap27 - Pituitary Adenylate Cyclase-Activating Polypeptide 38 protein
Pacap-38 protein
Pacap38 protein
ADCYAP1 protein

Information sourced from Uniprot.org

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