Nurr1 Positive Control peptide (STJ504495)
SPECIFICATIONS
General Information
| Short Description | Nurr1 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NR4A2 |
| Gene ID | 4929 |
| Uniprot ID | NR4A2_HUMAN |
Additional Info
| Tissue Specificity | Expressed in a number of cell lines of T-cell, B-cell and fibroblast origin. Strong expression in brain tissue. |
| Function | Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. |
| Peptide Name | Nuclear Receptor Subfamily 4 Group A Member 2Immediate-Early Response Protein NotOrphan Nuclear Receptor Nurr1Transcriptionally-Inducible Nuclear Receptor |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-4090294 |
| Cellular Localisation | CytoplasmNucleusMostly NuclearOxidative Stress Promotes Cytoplasmic Localization |
| Alternative Peptide Names | Nuclear Receptor Subfamily 4 Group A Member 2 proteinImmediate-Early Response Protein Not proteinOrphan Nuclear Receptor Nurr1 proteinTranscriptionally-Inducible Nuclear Receptor proteinNR4A2 proteinNOT proteinNURR1 proteinTINUR protein |
Information sourced from Uniprot.org