| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Myoregulin Blocking Peptide is synthetically produced from the 1-50 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | MRLN |
| Gene ID: | 100507027 |
| Uniprot ID: | MLN_HUMAN |
| Immunogen Region: | 1-50 |
| Immunogen: | Synthetic peptide taken within amino acid region 1-50 on human Myoregulin protein. |
| Function | Inhibits the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+), thereby acting as a key regulator of skeletal muscle activity. Its high expression in adult skeletal muscle, suggests that it constitutes the predominant regulator of ATP2A1/SERCA1 in adult skeletal muscle. Also inhibits the activity of ATP2A2/SERCA2 and ATP2A3/SERCA3. |
| Peptide Name | Myoregulin |
| Cellular Localisation | Sarcoplasmic Reticulum MembraneSingle-Pass Membrane Protein |
| Alternative Peptide Names | Myoregulin proteinMRLN proteinMLN protein |
Information sourced from Uniprot.org