Myoglobin Positive Control peptide (STJ504467)
SPECIFICATIONS
General Information
| Short Description | Myoglobin Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:1, 000 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | MB |
| Gene ID | 4151 |
| Uniprot ID | MYG_HUMAN |
Additional Info
| Function | Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity. |
| Peptide Name | MyoglobinNitrite Reductase MbPseudoperoxidase Mb |
| Database Links | Reactome: R-HSA-8981607 |
| Cellular Localisation | CytoplasmSarcoplasm |
| Alternative Peptide Names | Myoglobin proteinNitrite Reductase Mb proteinPseudoperoxidase Mb proteinMB protein |
Information sourced from Uniprot.org