| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | MYLK3 Positive Control for STJ501841 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:2, 500-1:5, 000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | MYLK3 |
| Gene ID: | 91807 |
| Uniprot ID: | MYLK3_HUMAN |
| Specificity: | This is positive control is recommended for use in combination with MYLK3 antibody STJ501841. |
| Immunogen: | Purified Protein |
| Tissue Specificity | Restricted to heart. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility. |
| Peptide Name | Myosin Light Chain Kinase 3Cardiac-Mybp-C-Associated Ca/Cam KinaseCardiac-Mlck |
| Cellular Localisation | Cytoplasm |
| Alternative Peptide Names | Myosin Light Chain Kinase 3 proteinCardiac-Mybp-C-Associated Ca/Cam Kinase proteinCardiac-Mlck proteinMYLK3 proteinMLCK protein |
Information sourced from Uniprot.org