| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
MRGX1 Blocking Peptide for STJ501799 is synthetically produced from the 280-330 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Mrgprx1 |
| Gene ID: |
282547 |
| Uniprot ID: |
MRGX1_RAT |
| Immunogen Region: |
280-330 |
| Specificity: |
This blocking peptide is recommended for use in combination with MRGX1 antibody, STJ501799 |
| Immunogen: |
Synthetic peptide taken within amino acid region 280-330 on rat MrgX1 protein. |
| Tissue Specificity | Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Associated preferentially with IB4 class of small-diameter somatosensory afferents (also known as nociceptors). |
| Function | Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception. |
| Peptide Name | Mas-Related G-Protein Coupled Receptor Member X1Sensory Neuron-Specific G-Protein Coupled Receptor 1 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Mas-Related G-Protein Coupled Receptor Member X1 proteinSensory Neuron-Specific G-Protein Coupled Receptor 1 proteinMrgprx1 proteinMrgc proteinMrgprc proteinMrgprc11 proteinSnsr proteinSnsr1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
