MRGX1 Blocking Peptide for STJ501799 peptide (STJ504384)

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STJ504384-250
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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : MRGX1 Blocking Peptide for STJ501799 is synthetically produced from the 280-330 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Mrgprx1
Gene ID: 282547
Uniprot ID: MRGX1_RAT
Immunogen Region: 280-330
Specificity: This blocking peptide is recommended for use in combination with MRGX1 antibody, STJ501799
Immunogen: Synthetic peptide taken within amino acid region 280-330 on rat MrgX1 protein.
Tissue Specificity Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Associated preferentially with IB4 class of small-diameter somatosensory afferents (also known as nociceptors).
Function Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. May regulate the function of nociceptive neurons by modulation of pain perception.
Peptide Name Mas-Related G-Protein Coupled Receptor Member X1
Sensory Neuron-Specific G-Protein Coupled Receptor 1
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Mas-Related G-Protein Coupled Receptor Member X1 protein
Sensory Neuron-Specific G-Protein Coupled Receptor 1 protein
Mrgprx1 protein
Mrgc protein
Mrgprc protein
Mrgprc11 protein
Snsr protein
Snsr1 protein

Information sourced from Uniprot.org

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