Mouse WNT6 protein (Recombinant) (N-His) (STJP010327)

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STJP010327
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse WNT6-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Wnt6
Gene ID: 22420
Uniprot ID: WNT6_MOUSE
Immunogen Region: Leu24-Leu364
Immunogen: Mus musculus (Mouse)
Post Translational Modifications Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Function Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Protein Name Protein Wnt-6
Database Links Reactome: R-MMU-3238698
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Protein Wnt-6 protein
Wnt6 protein
Wnt-6 protein

Information sourced from Uniprot.org