| Post Translational Modifications | N-glycosylated. |
| Function | Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. |
| Protein Name | V-Set Domain Containing T-Cell Activation Inhibitor 1B7 Homolog 4B7-H4Immune Costimulatory Protein B7-H4Protein B7s1T Cell Costimulatory Molecule B7x |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorExpressed At The Cell SurfaceA Soluble Form Has Also Been Detected |
| Alternative Protein Names | V-Set Domain Containing T-Cell Activation Inhibitor 1 proteinB7 Homolog 4 proteinB7-H4 proteinImmune Costimulatory Protein B7-H4 proteinProtein B7s1 proteinT Cell Costimulatory Molecule B7x proteinVtcn1 proteinB7h4 protein |
Information sourced from Uniprot.org
