| Tissue Specificity | Abundantly expressed in heart, brain, kidney and skeletal muscle. |
| Post Translational Modifications | VEGF-B186 is O-glycosylated. |
| Function | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. VEGF-B seems to be required for normal heart function in adult but is not required for proper development of the cardiovascular system either during development or for angiogenesis in adults. |
| Protein Name | Vascular Endothelial Growth Factor BVegf-BVegf-Related FactorVrf |
| Database Links | Reactome: R-MMU-114608Reactome: -MMU-194313Reactome: -MMU-195399 |
| Cellular Localisation | SecretedSecreted But Remains Associated To Cells Or To The Extracellular Matrix Unless Released By Heparin |
| Alternative Antibody Pair Names | Vascular Endothelial Growth Factor B antibody pairVegf-B antibody pairVegf-Related Factor antibody pairVrf antibody pairVegfb antibody pairVrf antibody pair |
Information sourced from Uniprot.org
