Mouse TOP2 (Topoisomerase II) Sandwich ELISA Kit Ready-To-Use Kit (STJE0019123)

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STJE0019123
€496.20 - €690.60
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Short Description :This TOP2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids..
Applications:ELISA
Reactivity:Mouse
Sensitivity:0.116ng/mL
Detection Limit:0.312-20ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:3 hrs
Gene Symbol:Top2a
Gene ID:21973
Uniprot ID:TOP2A_MOUSE
Immunogen Region:Ready-To-Use
Sample Type:tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Phosphorylation has no effect on catalytic activity. However, phosphorylation at Ser-1105 by CSNK1D/CK1 promotes DNA cleavable complex formation.
Function Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand. May play a role in regulating the period length of BMAL1 transcriptional oscillation.
Protein Name Dna Topoisomerase 2-Alpha
Dna Topoisomerase Ii - Alpha Isozyme
Database Links Reactome: R-MMU-4615885
Cellular Localisation Cytoplasm
Nucleus
Nucleoplasm
Nucleolus
Alternative ELISA Names Dna Topoisomerase 2-Alpha ELISA kit
Dna Topoisomerase Ii - Alpha Isozyme ELISA kit
Top2a ELISA kit
Top-2 ELISA kit
Top2 ELISA kit
output

Information sourced from Uniprot.org