• Mouse TNFRSF11B/Osteoprotegerin protein (Recombinant) (C-hFc&His) (STJP001144)
  • Mouse TNFRSF11B/Osteoprotegerin protein (Recombinant) (C-hFc&His) (STJP001144)
  • Mouse TNFRSF11B/Osteoprotegerin protein (Recombinant) (C-hFc&His) (STJP001144)
  • Mouse TNFRSF11B/Osteoprotegerin protein (Recombinant) (C-hFc&His) (STJP001144)
  • Mouse TNFRSF11B/Osteoprotegerin protein (Recombinant) (C-hFc&His) (STJP001144)
  • Mouse TNFRSF11B/Osteoprotegerin protein (Recombinant) (C-hFc&His) (STJP001144)

Mouse TNFRSF11B/Osteoprotegerin protein (Recombinant) (C-hFc&His) (STJP001144)

SKU:
STJP001144

Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse TNFRSF11B/Osteoprotegerin-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human TNFSF11 at 2 Mu g/mL (100 Mu L/well) can bind Recombinant Mouse TNFRSF11B with a linear range of 3-10 ng/mL.2. Measured by its ability to inhibit TRAIL-mediated cyto
Gene Symbol: Tnfrsf11b
Gene ID: 18383
Uniprot ID: TR11B_MOUSE
Immunogen: Recombinant Mouse TNFRSF11B/Osteoprotegerin Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Met1-Leu401) of mouse Osteoprotegerin/TNFRSF11B (Accession #NP_032790.3) fused with an Fc, 6×His tag at the C-
Function Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 11b
Osteoclastogenesis Inhibitory Factor
Osteoprotegerin
Database Links Reactome: R-MMU-5669034
Cellular Localisation Secreted
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 11b protein
Osteoclastogenesis Inhibitory Factor protein
Osteoprotegerin protein
Tnfrsf11b protein
Ocif protein
Opg protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance