Function | Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) and linolenoyl-CoA ((9Z,12Z,15Z)-octadecatrienoyl-CoA) as substrates. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa. |
Protein Name | Sterol O-Acyltransferase 2Acyl-Coenzyme A -Cholesterol Acyltransferase 2Acat-2Cholesterol Acyltransferase 2 |
Database Links | Reactome: R-MMU-8964038 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Protein Names | Sterol O-Acyltransferase 2 proteinAcyl-Coenzyme A -Cholesterol Acyltransferase 2 proteinAcat-2 proteinCholesterol Acyltransferase 2 proteinSoat2 proteinAcact-2 proteinAcat2 protein |
Information sourced from Uniprot.org