Mouse SGPP2 (Sphingosine-1-Phosphate Phosphatase 2) Sandwich ELISA Kit Kit (STJE0012144)

Mouse SGPP2 (Sphingosine-1-Phosphate Phosphatase 2) Sandwich ELISA Kit Kit (STJE0012144)

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STJE0012144
£476.50 - £651.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.073ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This SGPP2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Sgpp2
Gene ID: 433323
Uniprot ID: SGPP2_MOUSE
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in pancreatic islets. Expressed in lung, small interstince, colon, kideny and brain.
Post Translational Modifications
Function Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro (Probable). Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway. May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling. Plays a role in the regulation of pancreatic islet beta-cell endoplasmic reticulum stress and proliferation.
Protein Name Sphingosine-1-Phosphate Phosphatase 2
Sppase2
Spp2
Sphingosine-1-Phosphatase 2
Database Links Reactome: R-MMU-9845614
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Sphingosine-1-Phosphate Phosphatase 2 ELISA kit
Sppase2 ELISA kit
Spp2 ELISA kit
Sphingosine-1-Phosphatase 2 ELISA kit
Sgpp2 ELISA kit
output

Information sourced from Uniprot.org

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