| Short Description : | Recombinant-Mouse SERPIND1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 50mM Tris-HCl, 150mM NaCl, 5% Mannitol, 0.06% Tween 80, pH 8.0. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | Serpind1 |
| Gene ID: | 15160 |
| Uniprot ID: | HEP2_MOUSE |
| Immunogen: | Mus musculus (Mouse) |
| Immunogen Region: | Glu24-Ser478 |
| Post Translational Modifications | N-glycosylated.different glycan composition appears to lead to two forms of this protein (68 and 72 kDa). |
| Function | Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. |
| Protein Name | Heparin Cofactor 2Heparin Cofactor IiHc-IiProtease Inhibitor Leuserpin-2Serpin D1 |
| Database Links | Reactome: R-MMU-140837Reactome: -MMU-140875Reactome: -MMU-381426Reactome: -MMU-8957275 |
| Cellular Localisation | |
| Alternative Protein Names | Heparin Cofactor 2 proteinHeparin Cofactor Ii proteinHc-Ii proteinProtease Inhibitor Leuserpin-2 proteinSerpin D1 proteinSerpind1 proteinHcf2 proteinHcii protein |
Information sourced from Uniprot.org