• Mouse SELP/P-Selectin/CD62P protein (Recombinant) (C-His) (STJP001133)

Mouse SELP/P-Selectin/CD62P protein (Recombinant) (C-His) (STJP001133)

SKU:
STJP001133

£97.50 - £189.50
Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse SELP/P-Selectin/CD62P-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by the ability of the immobilized protein to support the adhesion of U937 cells. When 5 x 10E4 cells/well are added to SELP-coated plates (10 Mu g/mL and 100 Mu L/well) , approximately >40% cells will adhere specifically after 1 hour at 37 °
Gene Symbol: Selp
Gene ID: 20344
Uniprot ID: LYAM3_MOUSE
Immunogen: Recombinant Mouse SELP/P-Selectin/CD62P Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Trp42-Ala709) of mouse P-Selectin/CD62P (Accession #NP_035477.1.) fused with a 6×His tag at the C-terminus.
Function Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.
Protein Name P-Selectin
Cd62 Antigen-Like Family Member P
Granule Membrane Protein 140
Gmp-140
Leukocyte-Endothelial Cell Adhesion Molecule 3
Lecam3
Platelet Activation Dependent Granule-External Membrane Protein
Padgem
Cd Antigen Cd62p
Database Links Reactome: R-MMU-114608
Reactome: -MMU-202733
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names P-Selectin protein
Cd62 Antigen-Like Family Member P protein
Granule Membrane Protein 140 protein
Gmp-140 protein
Leukocyte-Endothelial Cell Adhesion Molecule 3 protein
Lecam3 protein
Platelet Activation Dependent Granule-External Membrane Protein protein
Padgem protein
Cd Antigen Cd62p protein
Selp protein
Grmp protein

Information sourced from Uniprot.org

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