Mouse RNLS/Renalase protein (Recombinant) (N-His) (STJP011147)

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STJP011147
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse RNLS/Renalase-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Rnls
Uniprot ID: RNLS_MOUSE
Immunogen Region: Ala18-Ile342
Immunogen: Mus musculus (Mouse)
Function Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Protein Name Renalase
Monoamine Oxidase-C
Mao-C
Mmao-C
Cellular Localisation Secreted
Alternative Protein Names Renalase protein
Monoamine Oxidase-C protein
Mao-C protein
Mmao-C protein
Rnls protein

Information sourced from Uniprot.org

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