Mouse REN/Renin protein (Recombinant-Active) (C-10*His) (STJP011806)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Active-Mouse REN/Renin-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8Ā°C for one week. Store at-20 to-80Ā°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its ability to cleave the fluorogenic peptide substrate 5-FAM/QXLā¢ 520. The specific activity is >20 pmol/min/Mu g, as measured under the described conditions. |
Target Information
| Gene Symbol | Ren1 |
| Gene ID | 19701 |
| Uniprot ID | RENI1_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Leu22-Arg402 |
Additional Info
| Function | Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| Protein Name | Renin-1AngiotensinogenaseKidney Renin |
| Database Links | Reactome: R-MMU-2022377 |
| Cellular Localisation | SecretedMembraneAssociated To Membranes Via Binding To Atp6ap2 |
| Alternative Protein Names | Renin-1 proteinAngiotensinogenase proteinKidney Renin proteinRen1 proteinRen proteinRen-1 protein |
Information sourced from Uniprot.org