| Short Description : | Recombinant-Active-Mouse REN/Renin-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to cleave the fluorogenic peptide substrate 5-FAM/QXL™ 520. The specific activity is >20 pmol/min/Mu g, as measured under the described conditions. |
| Gene Symbol: | Ren1 |
| Gene ID: | 19701 |
| Uniprot ID: | RENI1_MOUSE |
| Immunogen: | Mus musculus (Mouse) |
| Immunogen Region: | Leu22-Arg402 |
| Function | Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. |
| Protein Name | Renin-1AngiotensinogenaseKidney Renin |
| Database Links | Reactome: R-MMU-2022377 |
| Cellular Localisation | SecretedMembraneAssociated To Membranes Via Binding To Atp6ap2 |
| Alternative Protein Names | Renin-1 proteinAngiotensinogenase proteinKidney Renin proteinRen1 proteinRen proteinRen-1 protein |
Information sourced from Uniprot.org
