Mouse REG3b (Regenerating Islet Derived Protein 3 Beta) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018243)

SPECIFICATIONS
STJE0018243
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General Information

Short DescriptionThis REG3b Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma or other biological fluids..
ApplicationsELISA
ReactivityMouse
Sensitivity4.1pg/mL
Detection Limit9.37-600pg/mL
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Storage InstructionThe whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time3 hrs

Target Information

Gene SymbolReg3b
Gene ID18489
Uniprot IDREG3B_MOUSE
Immunogen RegionReady-To-Use
Sample Typeserum, plasma or other biological fluids.

Additional Info

Tissue Specificity Constitutively expressed in the small intestine, moderately in colon and at an extremely low level in healthy pancreas.
Post Translational Modifications Proteolytic processing by trypsin removes an inhibitory N-terminal propeptide and is essential for peptidoglycan binding and antibacterial activity.
Function Bactericidal C-type lectin which acts against several intestinal Gram-positive and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues. Acts as a hormone in response to different stimuli. Secreted by different cell types to activate its receptor EXTL3 and induce cell specific signaling pathways. In pancreas, is able stimulate cell proliferation.
Protein Name Regenerating Islet-Derived Protein 3-Beta
Reg-3-Beta
Pancreatitis-Associated Protein 1
Regenerating Islet-Derived Protein Iii-Beta
Reg Iii-Beta Cleaved Into - Regenerating Islet-Derived Protein 3-Beta 16.5 Kda Form - Regenerating Islet-Derived Protein 3-Beta 15 Kda Form
Database Links Reactome: R-MMU-6803157
Cellular Localisation Secreted
Found In The Apical Region Of Pancreatic Acinar Cells
Alternative ELISA Names Regenerating Islet-Derived Protein 3-Beta ELISA kit
Reg-3-Beta ELISA kit
Pancreatitis-Associated Protein 1 ELISA kit
Regenerating Islet-Derived Protein Iii-Beta ELISA kit
Reg Iii-Beta Cleaved Into - Regenerating Islet-Derived Protein 3-Beta 16.5 Kda Form - Regenerating Islet-Derived Protein 3-Beta 15 Kda Form ELISA kit
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output

Information sourced from Uniprot.org

Citations

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