Mouse Reg3b protein (Recombinant) (C-Fc) (STJP015256)
SPECIFICATIONS
HostMammalian Cells
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse Reg3b-C-Fc protein was developed from mammalian cells for the region C-Fc. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | Reg3b |
| Gene ID | 18489 |
| Uniprot ID | REG3B_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Met1-Gly175 |
Additional Info
| Post Translational Modifications | Proteolytic processing by trypsin removes an inhibitory N-terminal propeptide and is essential for peptidoglycan binding and antibacterial activity. |
| Function | Bactericidal C-type lectin which acts against several intestinal Gram-positive and Gram-negative bacteria. Lacks antibacterial activity against S.typhimurium. May play a role in protection against infection with S.enteritidis by inhibiting its translocation from the gut lumen into intestinal tissues and further extraintestinal tissues. Acts as a hormone in response to different stimuli. Secreted by different cell types to activate its receptor EXTL3 and induce cell specific signaling pathways. In pancreas, is able stimulate cell proliferation. |
| Protein Name | Regenerating Islet-Derived Protein 3-BetaReg-3-BetaPancreatitis-Associated Protein 1Regenerating Islet-Derived Protein Iii-BetaReg Iii-Beta Cleaved Into - Regenerating Islet-Derived Protein 3-Beta 16.5 Kda Form - Regenerating Islet-Derived Protein 3-Beta 15 Kda Form |
| Database Links | Reactome: R-MMU-6803157 |
| Cellular Localisation | SecretedFound In The Apical Region Of Pancreatic Acinar Cells |
| Alternative Protein Names | Regenerating Islet-Derived Protein 3-Beta proteinReg-3-Beta proteinPancreatitis-Associated Protein 1 proteinRegenerating Islet-Derived Protein Iii-Beta proteinReg Iii-Beta Cleaved Into - Regenerating Islet-Derived Protein 3-Beta 16.5 Kda Form - Regenerating Islet-Derived Protein 3-Beta 15 Kda Form proteinReg3b proteinPap proteinPap1 protein |
Information sourced from Uniprot.org