Function | Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. |
Protein Name | C-C Motif Chemokine 5MurantesSis-DeltaSmall-Inducible Cytokine A5T-Cell-Specific Protein Rantes |
Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594 |
Cellular Localisation | Secreted |
Alternative Antibody Pair Names | C-C Motif Chemokine 5 antibody pairMurantes antibody pairSis-Delta antibody pairSmall-Inducible Cytokine A5 antibody pairT-Cell-Specific Protein Rantes antibody pairCcl5 antibody pairScya5 antibody pair |
Information sourced from Uniprot.org