Host: |
Goat/Goat |
Applications: |
ELISA |
Reactivity: |
Mouse |
Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: |
This RANTES antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
Clonality: |
Polyclonal/Polyclonal |
Conjugation: |
Unconjugated/Biotin |
Formulation: |
Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
Purification: |
Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
Concentration: |
0.5 mg/mL |
Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
Gene Symbol: |
Ccl5 |
Gene ID: |
20304 |
Uniprot ID: |
CCL5_MOUSE |
Immunogen: |
Capture immunogen: Recombinant Mouse RANTES protein.Detection Immunogen: Recombinant Mouse RANTES protein. |
Function | Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. |
Protein Name | C-C Motif Chemokine 5MurantesSis-DeltaSmall-Inducible Cytokine A5T-Cell-Specific Protein Rantes |
Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594 |
Cellular Localisation | Secreted |
Alternative Antibody Pair Names | C-C Motif Chemokine 5 antibody pairMurantes antibody pairSis-Delta antibody pairSmall-Inducible Cytokine A5 antibody pairT-Cell-Specific Protein Rantes antibody pairCcl5 antibody pairScya5 antibody pair |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance