Name: Mouse PR3 (Proteinase 3) Sandwich ELISA Kit Kit (STJE0011634)
SKU: STJE0011634
Availability: InStock

Mouse PR3 (Proteinase 3) Sandwich ELISA Kit Kit (STJE0011634)

SKU:

STJE0011634

£456.50 - £625.50

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Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.058ng/mL
Detection Limit:	0.156-10ng/mL
Short Description :	This PR3 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids..

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Prtn3
Gene ID:	19152
Uniprot ID:	PRTN3_MOUSE
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.
Protein Name	Myeloblastin Proteinase 3 Pr-3
Database Links	Reactome: R-MMU-140875 Reactome: -MMU-6798695 Reactome: -MMU-6803157
Cellular Localisation	Lysosome Secreted Cell Membrane Peripheral Membrane Protein Extracellular Side Membrane Raft Localizes Predominantly To Azurophil Granules (Primary Secretory Granules) In Neutrophils Secreted Upon Neutrophil Stimulation By Tnf-Alpha Lipopolysaccharide (Lps) Fmlp And Cxcl8/Il8 Or During Neutrophil Transmigration Following Secretion Tethered To The Cell Membrane By Cd177
Alternative ELISA Names	Myeloblastin ELISA kit Proteinase 3 ELISA kit Pr-3 ELISA kit Prtn3 ELISA kit
output

Information sourced from Uniprot.org

Model	Name	Reactivity	Application
STJE0018020	Mouse PR3 (Proteinase 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018020)	Mouse	ELISA
STJE0011635	Rat PR3 (Proteinase 3) Sandwich ELISA Kit Kit (STJE0011635)	Rat	ELISA
STJE0003363	Human PR3 (Proteinase 3) Sandwich ELISA Kit (STJE0003363)	Human	ELISA
STJE0018021	Rat PR3 (Proteinase 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018021)	Rat	ELISA

Mouse PR3 (Proteinase 3) Sandwich ELISA Kit Kit (STJE0011634)