Mouse PDHa (Pyruvate Dehydrogenase Alpha) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017754)

Mouse PDHa (Pyruvate Dehydrogenase Alpha) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017754)

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STJE0017754
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.042ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This PDHa Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Pdha1
Gene ID: 18597
Uniprot ID: ODPA_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity In all tissues, but in very low amount in testis.
Post Translational Modifications Phosphorylation at Ser-232, Ser-293 and Ser-300 by PDK family kinases inactivates the enzyme.for this phosphorylation at a single site is sufficient. Phosphorylation at Ser-293 interferes with access to active site, and thereby inactivates the enzyme. Dephosphorylation at all three sites, i.e. at Ser-232, Ser-293 and Ser-300, is required for reactivation. Acetylation alters the phosphorylation pattern. Deacetylated by SIRT3.
Function The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Protein Name Pyruvate Dehydrogenase E1 Component Subunit Alpha - Somatic Form - Mitochondrial
Pdhe1-A Type I
Database Links Reactome: R-MMU-204174
Reactome: -MMU-5362517
Reactome: -MMU-9837999
Reactome: -MMU-9861559
Cellular Localisation Mitochondrion Matrix
Alternative ELISA Names Pyruvate Dehydrogenase E1 Component Subunit Alpha - Somatic Form - Mitochondrial ELISA kit
Pdhe1-A Type I ELISA kit
Pdha1 ELISA kit
Pdha-1 ELISA kit
output

Information sourced from Uniprot.org

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