| Tissue Specificity | Widely expressed at different developmental stages. Expressed at high level in the liver and the stomach, expressed at lower level in heart, spleen, thymus, small intestine, muscle, pancreas, uterus, and breast and expressed at very low level in brain, kidney, lung, testis, skin, adrenal gland and prostate gland. |
| Post Translational Modifications | |
| Function | Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. |
| Protein Name | Peroxisomal N(1-Acetyl-Spermine/Spermidine OxidasePolyamine Oxidase |
| Database Links | Reactome: R-MMU-141334Reactome: -MMU-351200Reactome: -MMU-9033241 |
| Cellular Localisation | PeroxisomeCytoplasm |
| Alternative ELISA Names | Peroxisomal N(1-Acetyl-Spermine/Spermidine Oxidase ELISA kitPolyamine Oxidase ELISA kitPaox ELISA kitPao ELISA kit |
| output | |
Information sourced from Uniprot.org
