Mouse OGG1 protein (Recombinant) (His-Tag) (STJP019333)
SPECIFICATIONS
HostE.coli
ImmunogenMouse
General Information
| Short Description | Recombinant-Mouse OGG1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 30% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Ogg1 |
| Gene ID | 18294 |
| Uniprot ID | OGG1_MOUSE |
| Accession Number | NP_035087 |
| Immunogen | Mouse |
| Immunogen Region | 1-345aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMLFRSWL PSSMRHRTLS SSPALWASIP CPRSELRLDL VLASGQSFRW KEQSPAHWSG VLADQVWTLT QTEDQLYCTV YRGDDSQVSR PTLEELETLH KYFQLDVSLA QLYSHWASVD SHFQRVAQKF QGVRLLRQDP TECLFSFICS SNNNIARITG MVERLCQAFG PRLIQLDDVT YHGFPNLHAL AGPEAETHLR KLGLGYRA |
Additional Info
| Tissue Specificity | Highest expression in testis. |
| Function | DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. |
| Protein Name | N-Glycosylase/Dna Lyase Includes - 8-Oxoguanine Dna Glycosylase - Dna-(Apurinic Or Apyrimidinic Site LyaseAp Lyase |
| Database Links | Reactome: R-MMU-110329Reactome: -MMU-110330Reactome: -MMU-110331Reactome: -MMU-110357Reactome: -MMU-5649702 |
| Cellular Localisation | NucleusNucleoplasmNucleus SpeckleNucleus MatrixTogether With Apex1 Is Recruited To Nuclear Speckles In Uva-Irradiated Cells |
| Alternative Protein Names | N-Glycosylase/Dna Lyase Includes - 8-Oxoguanine Dna Glycosylase - Dna-(Apurinic Or Apyrimidinic Site Lyase proteinAp Lyase proteinOgg1 protein |
Information sourced from Uniprot.org