| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.059ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This NUCB1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | Nucb1 |
| Gene ID: | 18220 |
| Uniprot ID: | NUCB1_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | Lymphoid cells as well as other somatic cells, such as liver and kidney cells. |
| Post Translational Modifications | |
| Function | Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins). |
| Protein Name | Nucleobindin-1 Calnuc |
| Database Links | Reactome: R-MMU-381426 Reactome: -MMU-8957275 |
| Cellular Localisation | Golgi Apparatus Cis-Golgi Network Membrane Peripheral Membrane Protein Lumenal Side Cytoplasm Secreted A Small Fraction Of The Protein May Be Cytoplasmic In Bone At Least Part Of It Is Found In The Extracellular Matrix And In The Culture Medium Of Calvaria Explants In Lupus Prone But Not In Normal Mice At Least Part Of It Is In The Serum Where It Induces The Formation Of Autoantibodies Including Anti-Dna Antibodies |
| Alternative ELISA Names | Nucleobindin-1 ELISA kit Calnuc ELISA kit Nucb1 ELISA kit Nuc ELISA kit Nucb ELISA kit |
| output |
Information sourced from Uniprot.org
