| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse NRTN-N-His-SUMO protein was developed from e. coli and has a target region of N-His-SUMO. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | Nrtn |
| Gene ID: | 18188 |
| Uniprot ID: | NRTN_MOUSE |
| Immunogen Region: | Arg99-Val195 |
| Immunogen: | Mus musculus (Mouse) |
| Function | Growth factor that supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Involved in the development of the neural crest. Might control the size of non-neuronal cell population such as haemopoietic cells. Acts by binding to its coreceptor, GFRA2, leading to autophosphorylation and activation of the RET receptor. Heparan sulfate-binding is required for signaling. |
| Protein Name | Neurturin |
| Database Links | Reactome: R-MMU-5673001Reactome: -MMU-8853659 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Neurturin proteinNrtn protein |
Information sourced from Uniprot.org