Mouse NECTIN4 protein (Recombinant) (C-His) (STJP015616)

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STJP015616
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Short Description :Recombinant-Mouse NECTIN4-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:Please contact us for further information.
Gene Symbol:Nectin4
Gene ID:71740
Uniprot ID:NECT4_MOUSE
Immunogen:Mus musculus (Mouse)
Immunogen Region:Met1-Ser347
Function Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Plays a role in the senescence-associated cell size enlargement via SFK/PI3K/Rac1 and thus promotes senescent cell survival. Also participates in the innate immune response by acting as a ligand for the receptor TIGIT to inhibit NK-cell activity.
Protein Name Nectin-4
Ig Superfamily Receptor Lnir
Nectin Cell Adhesion Molecule 4
Poliovirus Receptor-Related Protein 4
Database Links Reactome: R-MMU-418990
Reactome: -MMU-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Adherens Junction
Colocalizes With Afdn At Cadherin-Based Adherens Junctions
Alternative Protein Names Nectin-4 protein
Ig Superfamily Receptor Lnir protein
Nectin Cell Adhesion Molecule 4 protein
Poliovirus Receptor-Related Protein 4 protein
Nectin4 protein
Lnir protein
Prr4 protein
Pvrl4 protein

Information sourced from Uniprot.org

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